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Precipitation reaction is relatively less sensitive for the detection of

  • A.antigens
  • B.antigen-antibody complexes
  • C.antibodies
  • D.complement

Answer: C

Correct answer: antibodies

Precipitation uses soluble antigen, so a large amount of antibody must be present before enough antigen-antibody lattice forms to come out of solution and be seen. Agglutination, with the antigen already particulate, gives a visible result from far less antibody. This difference in sensitivity is the reason soluble antigens are commonly adsorbed onto carrier particles before testing.

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