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What are the three mechanisms to reduce blood in haemostasis in correct sequence?

  • A.Platelet Plug Formation → Vascular Spasm → Blood Clotting (Coagulation)
  • B.Vascular Spasm → Platelet Plug Formation → Blood Clotting (Coagulation)
  • C.Blood Clotting (Coagulation) → Platelet Plug Formation → Vascular Spasm
  • D.Blood Clotting (Coagulation) → Vascular Spasm → Platelet Plug Formation

Answer: B

The correct sequence is Vascular Spasm → Platelet Plug Formation → Blood Clotting (Coagulation).

When a vessel is cut, its smooth muscle contracts at once (vascular spasm), narrowing the vessel and reducing blood loss within seconds. Platelets then stick to the exposed collagen, release chemicals that attract more platelets, and form a temporary plug. Finally the coagulation cascade turns fibrinogen into fibrin, which reinforces the plug into a stable clot.

Every other order puts a slower step first. Coagulation takes minutes and depends on platelets already being in place, so it cannot come first, and the platelet plug forms after the vessel has constricted.

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