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Maturation promoting factor, which drives a cell into mitosis, is a complex of

  • A.cyclin B and its dependent kinase
  • B.p53 together with the Rb protein
  • C.tubulin and the motor protein dynein
  • D.two identical molecules of cyclin D

Answer: A

Its discovery in frog eggs showed that a diffusible factor could push a cell into division, and it was later identified as a cyclin-CDK pair. The finding linked embryology to yeast genetics. Two quite separate research traditions turned out to be studying one system.

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