Discussion
Streptococcus pyogenes can be differentiated from other haemolytic Streptococci on the basis of
Answer: A
Correct answer: Bacitracin sensitivity
A bacitracin disc is the classic presumptive test: S. pyogenes is sensitive to low-concentration bacitracin while most other beta-haemolytic streptococci are resistant, so a zone of inhibition around the disc identifies group A. Penicillin is useless as a differentiating test because all streptococci remain sensitive to it, which is fortunate therapeutically but unhelpful diagnostically.
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