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The visible degenerative changes produced in cultured cells by a virus are called

  • A.plaque count
  • B.titre
  • C.eclipse
  • D.cytopathic effect

Answer: D

Rounding, detachment, fusion and lysis of cells in a monolayer are collectively the cytopathic effect, and the pattern is characteristic enough to suggest which virus is present. Its appearance is the usual first indication that an inoculated culture is infected.

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