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Lactobacilli constitute the normal flora of

  • A.prepubertal vagina
  • B.adult vagina
  • C.post-menopausal vagina
  • D.none of these

Answer: B

Correct answer: adult vagina

Lactobacilli - Doderlein’s bacilli - colonise the vagina only when oestrogen causes the epithelium to lay down glycogen, which the organism ferments to lactic acid. That happens from puberty to the menopause, so the adult vagina is dominated by them and its pH is held around 4 to 4.5. Before puberty and after the menopause there is no glycogen, the lactobacilli are scanty, and the pH is near neutral, which is one reason the flora of those two age groups resembles each other more than either resembles the adult.

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