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To which category of drugs does Busulfan belong ?

  • A.Antibiotic
  • B.Alkylating agent
  • C.Antiviral
  • D.Antimetabolite

Answer: B

Busulfan is an alkylating agent.

Busulfan is an alkyl sulphonate. It attaches alkyl groups to DNA and cross-links its strands, which stops cell division. It acts strongly on the bone marrow, so it is used in chronic myeloid leukaemia and to condition patients before bone marrow transplantation.

It is not an antibiotic or an antiviral. Antimetabolites such as methotrexate and 5-fluorouracil work differently, by mimicking the building blocks of DNA.

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