Discussion
______ is a bactericidal drug used in treatment of tuberculosis.
Answer: C
The keyed answer is rifampicin.
Rifampicin is a first-line anti-tubercular drug that kills Mycobacterium tuberculosis by blocking its RNA synthesis. It is strongly bactericidal and also sterilises slowly multiplying bacilli, which makes it the backbone of short-course treatment.
Ethambutol and thioacetazone are bacteriostatic: they stop the bacilli multiplying without killing them. Ofloxacin is also bactericidal, but it is a second-line drug kept for drug-resistant tuberculosis, so the first-line bactericidal drug among the options is rifampicin.
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