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Antibody coated pathogens are recognized by effector cells through

  • A.CD4 receptor
  • B.F\(_{C}\) receptor
  • C.CD8 receptor
  • D.IFN gamma receptor

Answer: B

Antibody-coated pathogens are recognised through the F\(_{C}\) receptor.

An antibody binds the pathogen with its Fab arms, leaving the Fc (constant) tail pointing outward. Phagocytes, NK cells, mast cells and other effector cells carry Fc receptors that bind this tail, which triggers opsonic phagocytosis or antibody-dependent cell-mediated cytotoxicity.

CD4 and CD8 are co-receptors on T cells that bind MHC class II and class I molecules. The IFN-γ receptor binds a cytokine. None of them recognises antibody bound to a microbe.

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