Discussion
The most abundant class of immunoglobulins in serum is __________.
Answer: D
The most abundant serum immunoglobulin is IgG.
IgG makes up about three-quarters of the immunoglobulin in normal serum. It is the main antibody of the secondary immune response, it is the only class that crosses the placenta, and it neutralises toxins and opsonises microbes.
IgA is the main antibody of secretions (saliva, tears, milk) but is less abundant in serum. IgM is the large pentamer of the primary response, at around a tenth of the total, and IgD is present only in trace amounts, mainly on B cells.
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