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Identify the INCORRECT statement about the immunoglobulins (Ig)

  • A.IgM forms pentamer
  • B.IgA forms dimer
  • C.IgD is the most abundant immunoglobulin
  • D.IgE is associated with allergic reactions

Answer: C

The incorrect statement is IgD is the most abundant immunoglobulin.

IgG is the most abundant immunoglobulin in serum, about three quarters of the total. IgD is present only in trace amounts in serum; its main role is as an antigen receptor on the surface of mature naive B cells, alongside IgM.

The other statements are correct. Secreted IgM is a pentamer joined by a J chain. IgA in secretions such as saliva, tears and breast milk is a dimer. IgE binds to mast cells and basophils and triggers the release of histamine in allergic reactions.

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