Machine-translated by Google. Questions are authored in English.
Top

Discussion

Antibody titer refers to the :

  • A.Absolute amount of specific antibody
  • B.Avidity of specific antibody
  • C.Concentration of specific antibody
  • D.Highest dilution of antibody suitable to give a positive result in a test system.

Answer: D

Antibody titer is the highest dilution of antibody suitable to give a positive result in a test system.

A serum is diluted serially, for example 1:10, 1:20, 1:40 and so on, and each dilution is tested in an assay such as agglutination, haemagglutination inhibition or ELISA. The titer is the last dilution still giving a detectable positive reaction, usually reported as its reciprocal, such as 320. It is a relative measure used to compare samples, for example to show a rise in antibody between two samples in an infection.

It is not the absolute amount or the exact concentration of antibody, which need quantitative assays against a standard, and it is not avidity, the overall binding strength of a multivalent antibody.

No comment is present. Be the first to comment.
Loading…

Post your comment

Please log in or register to post a comment.