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Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto

  • A.bentonite particles
  • B.RBCs
  • C.latex particles
  • D.all of these

Answer: D

Correct answer: all of these

This is the standard device for gaining sensitivity: adsorb the soluble antigen onto a particle and the reaction becomes an agglutination, visible with far less antibody. Latex beads, bentonite and red cells are all used as carriers, the choice depending on the antigen and on how the result is to be read. The specificity comes from the antigen; the particle only makes the reaction visible.

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