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The antibody class found at highest concentrations in serum is

  • A.IgE
  • B.IgM
  • C.IgD
  • D.IgG

Answer: D

Correct answer: IgG

IgG makes up about 75 to 80 per cent of serum immunoglobulin, at roughly 8 to 16 g per litre. IgA follows, then IgM; IgD and IgE are present in trace amounts, IgE at only a few hundred nanograms per millilitre. That predominance, together with its long half-life and placental transfer, is why IgG carries most of the durable humoral protection.

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