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Monoclonal antibodies currently used clinically

  • A.Can protect against a wide variety of viruses and bacteria
  • B.Can reduce the inflammation associated with rheumatoid arthritis
  • C.Are derived from the plasma of individuals already immune to these organisms
  • D.Each have broad specificity for many antigenic determinants

Answer: B

Correct answer: Can reduce the inflammation associated with rheumatoid arthritis

Anti-tumour necrosis factor monoclonals such as infliximab and adalimumab are among the most widely used therapeutic antibodies, and they work precisely because a monoclonal has a single narrow specificity. The other options describe the opposite properties - broad cover, polyclonal origin from immune donors, multiple specificities - which belong to pooled immune globulin.

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