Discussion
Which of the following immunoglobulins makes the largest percentage in breast milk?
Answer: D
Correct answer: IgA
Secretory IgA is the dominant immunoglobulin in breast milk, as it is in every mucosal secretion. It is a dimer joined by the J chain and carrying the secretory component, which protects it from proteolysis in the infant gut. It is not absorbed but acts within the lumen, coating organisms and preventing their attachment to the mucosa.
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