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Which of the following antibodies is predominantly present in tears, saliva and mucous

  • A.IgM
  • B.IgG
  • C.IgE
  • D.IgA

Answer: D

Correct answer: IgA

Secretory IgA is the predominant antibody at every mucosal surface - tears, saliva, respiratory and intestinal secretions, and milk. It is secreted as a dimer with the J chain and acquires the secretory component as it crosses the epithelium, which protects it against the proteases it will meet on the other side.

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