Discussion
One principal function of the Class I and Class II major histocompatibility complex S proteins is to
Answer: C
Correct answer: present antigen for recognition by the T-cell antigen receptor
Both classes of major histocompatibility complex molecule are peptide-display platforms. Class I presents peptides from cytosolic proteins to CD8 T cells, class II presents peptides from endocytosed material to CD4 T cells. A T-cell receptor cannot see free antigen at all, which is why this presentation function is indispensable.
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