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T-cell receptors or antibodies react with antigens

  • A.because both are made by lymphocytes
  • B.because of complementary of molecular fit of both with antigen
  • C.because both 'have light chain and heavy chain polypeptides
  • D.cause histamine release

Answer: B

Correct answer: because of complementary of molecular fit of both with antigen

Both receptors work by shape complementarity: the binding site and the epitope fit together closely enough for many weak non-covalent interactions to act at once, and the sum of them gives the affinity. The specificity is a matter of fit, not of chemistry unique to either molecule, which is why two structurally unrelated receptor families can perform the same task.

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