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All of the following are true about antibodies, EXCEPT which one?

  • A.They fix complement.
  • B.They occur on the surface of B-lymphocyte
  • C.They predominate the primary immune response to antigen.
  • D.They are molecule with a single, defined amino acid sequence.

Answer: D

Correct answer: They are molecule with a single, defined amino acid sequence.

This is the false statement. Antibodies are enormously diverse: the variable domains are generated by the recombination of gene segments and further altered by somatic hypermutation, so a serum contains millions of different sequences. Only a monoclonal antibody, produced by a single clone, has one defined sequence. The other three statements are all true.

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