Machine-translated by Google. Questions are authored in English.
Top

Discussion

The major immunoglobulin family to which a particular immunoglobulin belongs can be determined by sequential analysis of the 110 amino acids beginning from the

  • A.Amino terminus of the light chain
  • B.Carboxy terminus of the light chain
  • C.Amino terminus of the heavy chain
  • D.Carboxy terminus of the heavy chain

Answer: D

Correct answer: Carboxy terminus of the heavy chain

The class is defined by the constant region of the heavy chain, and the constant region lies at the carboxy end. Sequencing from the amino terminus would give the variable domain, which differs between antibodies of the same class and is therefore no guide to it. The light chain carries no class information at all.

No comment is present. Be the first to comment.
Loading…

Post your comment

Please log in or register to post a comment.