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The immunoglobulin Joining chain (J-chain) is

  • A.only produced by T-Cells
  • B.only produced by neutrophils
  • C.associated with only multimeric forms of lgM and IgA
  • D.associated with IgE for histamine release

Answer: C

Correct answer: associated with only multimeric forms of lgM and IgA

The J chain is a small polypeptide that joins the monomer units of polymeric immunoglobulins - pentameric IgM and dimeric secretory IgA. Monomeric IgG, IgD and IgE have no J chain. It is made by the same plasma cell as the immunoglobulin, and it is also required for transport of IgA across the epithelium.

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