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All of the following are true EXCEPT

  • A.An epitope is a small portion of a macromolecule 
  • B. the variable region domains contain the antigen recognition site
  • C. an antigenic determinant is a paratope
  • D.The class of an immunoglobulin is determined by its heavy chain

Answer: C

Correct answer: an antigenic determinant is a paratope

This is the false statement. An antigenic determinant is an epitope, on the antigen; a paratope is the binding site on the antibody. The two are complementary partners, not synonyms. The other three statements are correct: an epitope is a small part of a macromolecule, the variable domains form the binding site, and the heavy chain determines the class.

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