Discussion
The immunoglobulin class which is the least abundant in the normal adult is
Answer: D
Correct answer: IgE
IgE is present in serum at only a few hundred nanograms per millilitre, five or six orders of magnitude below IgG. Most of it is not free in serum at all but bound to high affinity receptors on mast cells and basophils, which is exactly why so small a quantity can produce so violent a reaction.
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