Discussion
Match the antibiotics in Column A with their appropriate antimicrobial activity from Column B :
| Column A | Column B |
|---|---|
| I. Gatifloxacin | (a) Antifungal agent |
| II. Acyclovir | (b) Antibacterial agent |
| III. Mefloquine | (c) Antiviral agent |
| IV. Griseofulvin | (d) Antiprotozoal agent |
Answer: B
The correct matching is I-(b), II-(c), III-(d), IV-(a).
- Gatifloxacin is a fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV: antibacterial.
- Acyclovir is a guanosine analogue that inhibits herpesvirus DNA polymerase: antiviral.
- Mefloquine is used to prevent and treat malaria, caused by the protozoan Plasmodium: antiprotozoal.
- Griseofulvin is taken orally against dermatophyte (ringworm) infections: antifungal.
The other codes go wrong on at least one drug: one makes acyclovir antifungal, one makes gatifloxacin antiprotozoal, and one swaps acyclovir and mefloquine.
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