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The extrinsic pathway of apoptosis begins when

  • A.the mitochondria release all of their cytochrome c
  • B.the nucleus fragments itself into many small pieces
  • C.the cell entirely loses its own supply of oxygen
  • D.a death ligand binds a receptor at the surface

Answer: D

Immune cells use this route to instruct an infected or unwanted cell to die. The two pathways converge on the same executioner caspases despite their different starts. Convergence lets one execution machinery serve two quite different triggers.

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