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Periplasm is

  • A.the area between the inner and outer membranes of gram-negative bacteria
  • B.the area between the inner and outer membranes of Gram-positive bacteria
  • C.the interior portion of mitochondria
  • D.the area outside the cell membrane that is influenced by the polymers

Answer: A

Correct answer: the area between the inner and outer membranes of gram-negative bacteria

The periplasm is the compartment between the plasma membrane and the outer membrane, and it contains the thin peptidoglycan layer along with binding proteins, hydrolytic enzymes and the β-lactamases that destroy penicillin. Gram-positive cells have no outer membrane, so no true periplasm.

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