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In which of the following, lipo-polysaccharide is a major constituent of outer membrane of the cell wall?

  • A.Gram-positive bacteria
  • B.Gram-negative bacteria
  • C.Fungi
  • D.None of these

Answer: B

Correct answer: Gram-negative bacteria

Lipopolysaccharide makes up the outer leaflet of the gram-negative outer membrane. Its lipid A portion is the endotoxin responsible for fever and shock in gram-negative sepsis, and its O-antigen the basis of serotyping. Gram-positive walls have no outer membrane, and fungi have no LPS at all.

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