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Which one of the following statements is CORRECT for Mycoplasma?

  • A.Their cells are of definite shape.
  • B.They are resistant to lysis by osmotic shock.
  • C.Their growth is not inhibited by penicillin.
  • D.They are nonpathogenic to human.

Answer: C

The correct statement is: their growth is not inhibited by penicillin.

Mycoplasmas have no cell wall. Penicillin acts by blocking the cross-linking of peptidoglycan in the cell wall, so it has no target in a mycoplasma.

The lack of a wall also explains why the other statements are wrong. Without a rigid wall, mycoplasma cells are pleomorphic, of no definite shape, and they are sensitive to lysis by osmotic shock, being protected only by a sterol-containing membrane. They are not harmless either: Mycoplasma pneumoniae causes atypical pneumonia in humans and M. genitalium causes urethritis.

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