Discussion
Which of this bacteria is resistant to penicillin as it lacks a cell wall?
Answer: C
Correct answer: Mycoplasmas
Penicillin blocks the cross-linking of peptidoglycan, so it can only act on a cell that is building a wall. Mycoplasmas have none - only a sterol-strengthened membrane - so the drug has nothing to attack. Spirochaetes, cyanobacteria and bdellovibrios all have walls.
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