Discussion
Which of the following statements about the Fc fragment of an antibody is not true?
Answer: A
Correct answer: posses antigen combining activity
Antigen binding is the work of the Fab fragments, whose variable regions form the binding sites. The Fc fragment is the constant stem, and it carries the effector functions instead: complement fixation, placental transfer of IgG, and binding to cells - skin fixation by IgE, and opsonisation through Fc receptors on phagocytes.
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