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Negative result of the complement fixation reaction is expressed in

  • A.complete inhibition of haemolysis
  • B.complete haemolysis
  • C.haemagglutination
  • D.inhibition of haemagglutination

Answer: B

Correct answer: complete haemolysis

A negative result means antigen and antibody did not correspond, so no complex formed and the complement was not fixed. It is still free when the indicator system is added, and it lyses the sensitised red cells - complete haemolysis, giving a clear red solution.

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