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Which one of the following statements about endotoxins is false?

  • A.they are heat stable
  • B.protein-polysaccharide-lipid complex in nature
  • C.action is often enzymatic
  • D.is produced by Gram-negative bacteria

Answer: C

Correct answer: action is often enzymatic

That statement is false. Endotoxin is the lipid A of lipopolysaccharide, and it acts not as an enzyme but by triggering the host’s own inflammatory cascade - the cytokines that produce fever and shock. Exotoxins are the ones with enzymatic action. The other three statements are true: endotoxin is heat stable, it is a lipopolysaccharide-protein complex, and it comes from gram-negative bacteria.

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