Discussion
Which one is not the properties of ideal fixative? (Choose the most appropriate option from below)
Answer: D
The property an ideal fixative does not have is providing hyper-osmotic conditions to the tissues.
A fixative should preserve cells as close as possible to their living state. A hyperosmotic solution draws water out of cells and shrinks them, distorting the morphology the pathologist needs to see, so a good fixative is roughly isotonic.
The other three are genuine qualities of an ideal fixative: it should penetrate tissues and cells rapidly and evenly, it should not make the tissue excessively hard to cut, and it should be cheap and easily available. Formalin is widely used precisely because it meets these well.
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