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Zinc is essential for the function of

  • A.carboxypeptidase A.
  • B.chlorophyll a.
  • C.myoglobin.
  • D.vitamin B12.

Answer: A

Zinc is essential for carboxypeptidase A.

Carboxypeptidase A is a pancreatic exopeptidase that removes C-terminal amino acids, and it is a classic zinc metalloenzyme: a Zn2+ ion, held by two histidines and a glutamate, polarises the carbonyl of the peptide bond and activates a water molecule for the attack.

The other molecules use different metals. Chlorophyll a has magnesium at the centre of its chlorin ring; myoglobin carries iron in its haem group; and vitamin B12 (cobalamin) is built around cobalt.

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