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The oxidation of one molecule of NADH in mitochondria results in formation of

  • A.Two molecules of ATP
  • B.Five molecules of ATP
  • C.Three molecules of ATP
  • D.One molecule of ATP

Answer: C

The key's answer is Three molecules of ATP.

NADH from the mitochondrial matrix passes its electrons to complex I of the electron transport chain. The classical textbook value, based on a P/O ratio of 3, is that this yields three ATP, against two for FADH2, which enters at complex II.

Modern measurements give a lower figure of about 2.5 ATP per NADH, but that is not among the options, so the textbook value of three is the one the question expects. Two is the figure for FADH2, and five and one fit neither.

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