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The following refers to a recent development in technology. "It makes it possible to easily alter DNA sequences and modify Gene function. It can therefore correct genetic defects and improve crops, but with associated ethical problems."

Which of the following is the recent development referred to above ?

  • A.DNA Bar-coding
  • B.CRISPR
  • C.P53
  • D.Terminator

Answer: B

The development described is CRISPR.

CRISPR-Cas9 is a gene-editing technique adapted from a bacterial immune defence. A guide RNA directs the Cas9 enzyme to a chosen DNA sequence, where it cuts the DNA so that genes can be disabled, corrected or replaced. It is cheap and precise enough to be used to correct genetic defects and improve crops, and it raises ethical questions, especially over editing human embryos. Its developers, Jennifer Doudna and Emmanuelle Charpentier, received the 2020 Nobel Prize in Chemistry.

DNA barcoding identifies species from a short standard gene region. p53 is a tumour-suppressor gene. 'Terminator' technology makes seeds sterile so they cannot be replanted. None of them edits genes at will.

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