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Chromosomes contain ____.

  • A.Protein only
  • B.DNA and protein
  • C.DNA, RNA and histone
  • D.DNA, RNA, histone and non-histone proteins

Answer: B

The answer is DNA and protein.

A chromosome is made of chromatin, which is DNA wound around and packed by proteins. The proteins are of two kinds: histones, around which the DNA is coiled to form nucleosomes, and non-histone proteins, which include structural and regulatory proteins. So chromosomes are, in the standard textbook phrase, made of DNA and protein.

'Protein only' leaves out DNA, the genetic material itself. 'DNA, RNA and histone' leaves out the non-histone proteins. The last option lists components found in chromatin, but RNA is only a small, transient part (transcripts being made on it) rather than a structural constituent, so the model answer takes the two main components, DNA and protein.

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