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In human beings, disorder caused due to trisomy of 21st chromosome is :

  • A.Turner Syndrome
  • B.Down Syndrome
  • C.Super Female Syndrome
  • D.Klinefelter Syndrome

Answer: B

Trisomy of chromosome 21 causes Down Syndrome.

A person with Down syndrome has three copies of chromosome 21 instead of two (47 chromosomes in all), usually because the chromosomes failed to separate during egg or sperm formation. It causes intellectual disability, characteristic facial features and a higher risk of heart defects.

Turner syndrome is a missing X chromosome (45,X), Klinefelter syndrome is an extra X in a male (47,XXY), and 'super female' (triple X) is 47,XXX. All three involve sex chromosomes, not chromosome 21.

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