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All the following vaccines are examples of attenuated or inactivated whole pathogen vaccines, except :

  • A.Rabies vaccine
  • B.Tetanus vaccine
  • C.Oral polio vaccine (OPV)
  • D.Hepatitis A vaccine

Answer: B

The exception is the Tetanus vaccine.

The tetanus vaccine is a toxoid: it contains the tetanus toxin made harmless by chemical treatment, not the bacterium itself. It teaches the body to neutralise the toxin, which is what causes the disease.

The other three are whole-pathogen vaccines. The rabies vaccine and the hepatitis A vaccine contain inactivated (killed) virus, and the oral polio vaccine contains live attenuated (weakened) poliovirus.

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