Discussion
Agglutination test for Brucella mainly identifies which class of antibodies?
Answer: B
Correct answer: IgM
The plain agglutination test detects chiefly IgM, which is the earliest antibody produced and, being pentameric, by far the most efficient agglutinator - a single molecule can bridge several bacteria. That is precisely why the mercaptoethanol variant exists: removing the IgM contribution leaves the IgG titre, which carries the different information described above.
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