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State whether the following is true or false.
Mycoplasma contamination is easily spotted by cloudiness in the medium.

  • A.False only at small scales
  • B.True
  • C.False
  • D.True only at large scales

Answer: C

The organisms are far too small to make the medium turbid, so a heavily contaminated culture can look entirely normal. This is exactly what makes them a serious problem for reproducible work. Absence of visible signs is not evidence of a clean culture.

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