Discussion
Assertion (A): A laboratory keeps frozen stocks of a cell line at several passage numbers.
Reason (R): Cells change with continued passaging, so an early stock can be recovered if needed.
Answer: A
Correct answer: Both A and R are true, and R is the correct explanation of A
Both are true and the reason gives the purpose. Cells drift with passage: they accumulate genetic and epigenetic changes, subpopulations outgrow others, and behaviour shifts. Banking vials at intervals means work can be restarted from a defined early passage rather than continuing with cells that no longer match those used at the beginning, which is what makes results comparable over years.
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