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Specific oxygen consumption rates for mammalian cells are in the range of (where n and prepresents to nano and pico respectively)

  • A.0.05-5 nmol of O2/cell/h
  • B.5 - 10 nmol of O2 /cell/h
  • C.0.05-5 pmol of O2/cell/h
  • D.5 - 10 pmol of O2/cell/h

Answer: C

Correct answer: 0.05-5 pmol of O2/cell/h

Mammalian cells consume oxygen at about 0.05-5 picomoles per cell per hour. It is a small figure per cell but a demanding one in aggregate: oxygen is poorly soluble in water, so at high cell densities supplying it becomes the limiting factor in bioreactor design.

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