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How does CO2 help in the cell metabolism during cell culture?

  • A.It participates in the de novo synthesis of purines and pyrimidines
  • B.Helps in cell respiration
  • C.For monitoring pH of the culture
  • D.All of the above

Answer: A

Correct answer: It participates in the de novo synthesis of purines and pyrimidines

CO2 is not merely a waste gas: as bicarbonate it is a substrate for carboxylation reactions, including the de novo synthesis of purines and pyrimidines and of fatty acids. That is why cultures are kept in a CO2 atmosphere - though it also maintains the bicarbonate buffer and hence the pH.

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