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The restriction point, at which a cell commits to completing the cycle, lies in

  • A.metaphase of mitosis
  • B.late G1 phase
  • C.early S phase
  • D.late G2 phase

Answer: B

Past this point the cell no longer depends on external growth signals and will finish the cycle. It is the principal decision point, and its control is lost in most cancers. Yeast geneticists called the equivalent point START when they first found it.

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