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Cyclin-dependent kinases drive the cell cycle by

  • A.binding directly to the centromere of each chromosome
  • B.producing the ATP that division requires
  • C.phosphorylating target proteins when bound to a cyclin
  • D.cutting DNA at specific recognition sequences

Answer: C

The kinase is present at a steady level but inactive on its own, so activity follows the rise and fall of its partner cyclin. This is how a constant enzyme produces a cyclical output. Regulating the partner rather than the enzyme is a recurring trick in biology.

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