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A tumour suppressor gene differs from an oncogene in that a tumour suppressor

  • A.normally restrains cell division
  • B.normally promotes cell division
  • C.is present only in cancer cells
  • D.has no function in a healthy cell

Answer: A

Cancer results from losing both copies of a tumour suppressor or from gaining an overactive version of a proto-oncogene. The two therefore behave quite differently in inheritance. An inherited oncogene mutation is dominant, a suppressor loss recessive at the cell level.

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