Discussion
State whether the following is true or false.
Genes controlling the cell cycle are broadly conserved between yeast and humans.
Answer: C
Correct answer: True
The conservation is close enough that human cyclin-dependent kinase genes can rescue yeast mutants lacking their own. That is how the machinery was identified: the cdc mutants of budding and fission yeast defined the components, and the human counterparts were then found by complementation - work that earned the 2001 Nobel Prize and that underlies the cell cycle drugs now used in oncology.
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