Discussion
Assertion (A): A cell with unreplicated DNA does not normally enter mitosis.
Reason (R): The G2 checkpoint detects incomplete replication and blocks progression.
Answer: B
Correct answer: Both A and R are true, and R is the correct explanation of A
Both are true and the reason names the mechanism. The G2 checkpoint monitors whether replication is complete and whether the DNA is damaged, and it holds the cyclin-dependent kinase driving mitotic entry inactive until both are satisfied. Entering mitosis with unreplicated DNA would tear the chromosomes apart at anaphase, so the block is essential rather than merely prudent.
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